Description of Individual Course Units
Course Unit CodeCourse Unit TitleType of Course UnitYear of StudySemesterNumber of ECTS Credits
DİŞ217201421BIOCHEMISTRYCompulsory234
Level of Course Unit
First Cycle
Objectives of the Course
The aim of the course is • Studying biochemical structures of molecules appearing in biological systems (such as protein, carbohydrate, lipid and nucleic acid) and their interactions. • Studying synthesize and catabolic mechanisms of macro and micro molecules synthesized in the organism and their functions. • Using biochemical principles of health sciences and related fields, this area is to create and understanding about the ability of solving these problems as biochemical point of view. • Orienting knowledge acquisition and evaluation skills
Name of Lecturer(s)
Doç. Dr. Diler US ALTAY
Learning Outcomes
1Realizing basic biochemical principles and the relationship between various molecules and their chemical reactions occurring on viable cells and organisms
2Realizing the structure of carbohydrate, lipid and proteins and their functions on biochemical metabolism.
3Developing skills to identify structural and functional changes of organ systems in case of various diseases
4Realizing the structure of enzymes
Mode of Delivery
Formal Education
Prerequisites and co-requisities
None
Recommended Optional Programme Components
None
Course Contents
• Definition and subject of biochemistry • Solutions, Weak acids, Weak bases • Introduction to metabolism • Principles of free energy and thermodynamics • Amino acids • Protein structures and structure analysis • Nucleotides and their chemical structures • Structure and function of myoglobin and hemoglobin • Fibrous proteins • Enzymes • The structure of carbonhydrates Glycolysis Pyruvate metabolism and TCA cycle Pentosephosphate pathway Uronic acid pathway Gliconeogenesis Glycogen metabolism Metabolism of monosaccharides Electron transport chain and Oxidative phosphorylation Colorimetre Lipids and Lipoproteins Oxidation of fatty acids Synthesis of fatty acids Prostaglandins, and ketone bodies Triglycerides synthesis and catabolism Reaction of Lipids Phospholipids and glycolipids synthesis Cholesterol synthesis and catabolismc Synthesis of bile acids and salts, and catabolismc
Weekly Detailed Course Contents
WeekTheoreticalPracticeLaboratory
1Definition and subject of biochemistry
2Solutions, Weak acids, Weak bases
3Weak acids, bases, pH and buffers
4Introduction to metabolism, principles of free energy and thermodynamics
5Amino acids
6Protein structure and structure analysis
7Nucleotides and their chemical structures
8The reactions of aminoacides
9Enzymes
10Enzymes
11Fıbrous and globular proteıns
12Midterm Exam
13Activity of Enzymes
14Activity of Enzymes
15Structure of carbonhydrates
16The reactions of carbonhydrates
17Glycolysis
18Pyruvate metabolism and TCA cycle
19Pentosephosphate pathway
20Uronic acid pathway Gliconeogenesis
21Glycogen metabolism Metabolism of monosaccharides
22Electron transport chain and Oxidative phosphorylation
23Colorimetre
24Lipids and Lipoproteins
25Oxidation of fatty acids
26Synthesis of fatty acids
27Prostaglandins, and ketone bodies Triglycerides synthesis and catabolism
28Reaction of Lipids
29Midterm Exam
30Phospholipids and glycolipids synthesis
31Cholesterol synthesis and catabolism Synthesis of bile acids and salts, and catabolism
32Final
Recommended or Required Reading
Harvey, Champe, Lippincott Biyokimya N.V. Bhagavan, Medical Biochemistry D.N. Lehninger, Principles of Biochemistry R.K. Murray, Harper Biyokimya
Planned Learning Activities and Teaching Methods
Assessment Methods and Criteria
Term (or Year) Learning ActivitiesQuantityWeight
SUM0
End Of Term (or Year) Learning ActivitiesQuantityWeight
SUM0
Yarıyıl (Yıl) İçi Etkinlikleri60
Yarıyıl (Yıl) Sonu Etkinlikleri40
SUM100
Language of Instruction
Turkish
Work Placement(s)
None
Workload Calculation
ActivitiesNumberTime (hours)Total Work Load (hours)
Midterm Examination122
Final Examination122
Makeup Examination122
Laboratory14228
Self Study30390
TOTAL WORKLOAD (hours)124
Contribution of Learning Outcomes to Programme Outcomes
PO
1
PO
2
PO
3
PO
4
PO
5
PO
6
PO
7
PO
8
PO
9
PO
10
PO
11
LO112522111112
LO212522111112
LO312522111112
LO412522111112
* Contribution Level : 1 Very low 2 Low 3 Medium 4 High 5 Very High
 
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