Description of Individual Course Units
Course Unit CodeCourse Unit TitleType of Course UnitYear of StudySemesterNumber of ECTS Credits
OTF200201911CLASS-IICompulsory2358
Level of Course Unit
First Cycle
Objectives of the Course
MUSCLE AND NERVE TISSUES I. COMMITTEE To teach the theoretical and practical knowledge about the skeletal muscles The histology of muscle and nerve tissues to teach. Introduction to the embryology, gametogenesis, I., II. ve III. weeks of the development, embryologic and fetal period, fetal membranes, placenta and congenital malformations to teach. To provide the information about general and cellular organization of Nervous system, firing and conduction of an action potential in excitable cells and contraction mechanisms in skeletal, cardiac and smooth muscle cells. The learning of types of muscle, muscle proteins, the biochemical basis of muscle contraction in the human body and the main energy sources used in muscle. The learning of synaptic communication, neurotransmitters, neurohormones, brain metabolism and the brain chemical content. To teach the structural properties and functions of proteoglycans, fibronectin, kollageni elastin and other extracellular matrix proteins and epitelial cells. Learning general characteristics , vectorings, diagnosis, treatment and prevention methods of the Arthropods To learn skills of basic adult life support To Learn skills of pediatric life support. Gain to skills to intervene for choking. BLOOD LYMPH CIRCULATION and THE IMMUNE SYSTEM II. COMMITTEE To teach information about peripheral artery, nerve and vein Learning hematopoesis, the examination of blood components and structures found on the lymphoreticular organs To teach the blood tissue structure, its components and physiological functions The learningf the synthesis steps, the biochemical functions at the defending and hemoastaz of blood cells The learning of hemostasis and thrombosis, coagulation cascade, intrinsic, extrinsic and common pathway, anticoagulants and fibrinolysis. To teach the function and properties of plasma proteins and immunoglobulins, to teach evaluation of the laboratory tests used for diagnosis and treatment in diseases The learning of the basic concepts of functions and regulation of immune The learning of the general characteristics of immune responses The learning of the fungal infections The learning of serological methods of diagnosis Learning of diagnosis, treatment and prevention methods of the protozoons and trematodes living in the circulation of the blood-lymph The evaluation of circulatory system after medical education Examination of the respiratory system CIRCULATORY AND RESPIRATORY SYSTEMS III. COMMITTEE To theoretical and practical knowledge about the circulatory and respiratory system The development and histology of the respiratory system, heart and vessels to teach. To teach the normal structure and functions of heart and vessel system and properties of hemodynamics To provide the knowledge about the normal structure, functions, regulations of the respiratory system, properties of gas exchange and transport The learning the respiratory and metabolic acid-base disturbances, and how works to buffer systems in the body acting. This course is designed to give students an understanding of the fundamental aspects of free radicals and their role in disease and antioxidant defence systems against free radicals The learning of the basic properties of the microorganisms of medical importance The learning of this pathology formed tissues and organs of microorganisms The learning of infectious disease agents (bacteria, viruses), the clinical findings General characteristics of the blood and tissue nematodes , diagnosis, treatment and prevention methods The importance of hand hygiene and the prevention of Hospital Infections with considerations to learn the importance of hand washing, wearing sterile gloves learning method DIGESTIVE SYSTEM AND METABOLISM IV. COMMITTEE To teach theoretical and practical knowledge about the digestive system and organs The examination of the histology and function of the component parts of the digestive system To teach the normal structure and functions of organs involved in food intake, digestion and absorption, the mechanisms of digestion and absorption The learning the digestion and passage of nutrients into the bloodstream, blood sugar regulation, clinical diagnostic criteria for diabetes mellitus and complications involved in the biochemical processes and the synthesis of lipoproteins circulating roles and biochemical mechanisms that lead to atherosclerosis. The learning of doing oral glucose tolerance test. The learning of distribution of iron in the body, transport, storage, metabolism, balance of iron and iron metabolism associated diseases biochemical basis in the organism. The learning of adipose tissue, regulation of metabolism in adipose tissue, adipose tissue hormones, biochemical basis of obesity and the metabolic syndrome. The learning of reactions and disorders regulation of the metabolism of monosaccharides. To explain disorder of amino acid and protein metabolism and to explain the metabolism of the bilirubin, bile pigments and disorders of the bilirubin metabolism. To teach the functions of liver, to teach xenobiotics and molecular structures, xenobiotic biotransformations and enzymes The learning of the basic properties of the microorganisms of medical importance The learning of this pathology formed tissues and organs of microorganisms The learning of infectious disease agents (bacteria, viruses), the clinical findings Learning the diagnosis, treatment and prevention methods of the parasites that cause infections in the digestive system History taking and physical examination method Emergency concept and basic principles of learning NEUROCOMMITTEE V. COMMITTEE To teach the theoretical and practical knowledge about the nervous system The development of the nerve system to teach. The development and histology of the eye, ear and skin to teach. To teach the basic structure and functions of the CNS and sensory organs, its relationship with other systems in addition to the principles of perception and transmission the stimulus. The learning of laboratory analysis, sample collection, and clinical correlations of conditions of CSF (cerebrospinal fluid) and other body fluids. To explain the structural properties of the eye, to explain mechanisms of apopitotic that trigger cell death. The learning of the basic properties of the microorganisms of medical importance The learning of this pathology formed tissues and organs of microorganisms The learning of infectious disease agents (bacteria, viruses), the clinical findings Learning the general characteristics of free pathogenic amoeba, their diagnosis, treatment and prevention methods To appraise skills of intravenous injection Gain to skills of intramuscular injection. To learn forensic examination and forensic report writing ENDOCRİNE AND UROGENITAL SYSTEM VI. COMMITTEE To teach the theoretical and practical knowledge about the endocrine and urogenital system Histological and developmental evoluations of the contenents of endocrinal organs and urogenital system organs To provide the knowledge about the renal functions in fluid-electrolyte balance, acid-base balance, regulation of blood pressure regulation and removing waste materials. To provide the knowledge about the endocrine organs involved in regulation of the basic body functions, growth-development and reproduction, and action mechanisms of hormones that mediate the endocrine functions The learning the structure, synthesis, function and disorders of the thyroid hormones. The learning of kidney function tests, glomerular filtration rate (GFR), the factors affecting GFR, creatinine clearance, and other tests. The learning determination of creatinine in urine and blood, and the calculation of creatinine clearance. The learning of biochemical properties of the urine, physical and chemical analysis, analysis of the influence interferences and biochemical and clinical significance of urine analysis. The learning of urine physical and chemical structures and microscopic urine analysis. The learning of the biochemical basis of calcium and phosphorus metabolism, hormones, and disorders. The learning of biochemical principles of gonad’s steroid hormones and disorders. To explain structure, synthesis, function, and action mechanism of hormones and to explain function of the hormones secreted by the endocrine glands such as the pituitary and hypothalamus To explain the function and mehabolic effects of the adrenal hormones and pancreatic hormones. Learning the general characteristics of the Trichomonases , their diagnosis, treatment and prevention methods BIOLOGICAL BASIS OF DISEASES VII. COMMITTEE Learning the general characteristics of protozoon and helmints, their clinical features, diagnosis, treatment and prevention methods, The learning of relations host with bacteria The learning of Rickettsia and Chlamydia infections, The learning of biochemical analysis affecting the preanalytical factors Biochemical parameters to distinguish differences in childhood and old age, Basic information about infectious diseases, and clinical differences in approach to learning, The mechanisms of drug action, pharmacokinetic and pharmacodynamic drug interactions to teach, Teaching of the; definition of the medical pathology, laboratory technics, areas of the clinical and laboratory implementation, cell injury, adaptation, inflammation, healing and repair, impact of environmental factors in the development of the disease, intracellular accumulations, classifications and degeneration
Name of Lecturer(s)
Prof. Dr. Ahmet Bayrak Prof. Dr. Ahmet Kaya Prof. Dr. Havva Erdem Prof. Dr. Niyazi Taşçı Prof. Dr. Orhan Bas Prof. Dr. Özgür Enginyurt Prof. Dr. Tevfik Noyan Prof. Dr. Tülin Bayrak Doç. Dr. Ali Aslan Doç. Dr. Ebru Çanakçı Doç. Dr. M. Kerem Çalgın Doç Dr. Nilay Taş Doç.Dr. Pınar Naile Gürgör Doç. Dr. Selma Cırrık Doç. Dr. Ülkü Karaman Doç. Dr. Yasemin KAYA Doç.Dr. Yeliz Çetinkol Dr. Öğr. Üyesi Ali Aslan Dr. Öğr. Üyesi Arzu Altunçekiç Yıldırım Dr. Öğr. Üyesi Atakan Savrun Dr. Öğr. Üyesi Hatice Hancı Dr. Öğr. Üyesi Emine Yurdakul Ertürk Dr. Öğr. Üyesi Evren Şavlı Dr. Öğr. Üyesi Muhammet Değirmenci Dr. Öğr. Üyesi Mürüvvet A. Çelik Dr. Öğr. Üyesi Zübeyr Cebeci
Learning Outcomes
1Comprehend the significance of the bioelectrical potentials, signal transduction pathways, neurotransmission and neuromodulation in information processing, interaction / communication of the nervous system within itself and with the other organ systems, get to know the major neurotransmitter systems, and relate them to functions and behavior.
2Be able to define the histological and anatomical structures of joint, bone, muscle, and explain their physiological, biochemical, biophysical and behavioral mechanisms
3Understand the evolutional and developmental foundations of locomotion and conceptualize the human biomechanics.
4Describe the functions of the basic structures in blood,
5Recognize the biochemical processes concerning oxygen and hemoglobin in blood,
6Explain the structure and functions of the hematopoietic organs,
7Explain the functions of the heart and major vessels on the basis of their anatomical and histological properties,
8Explain the major structures and processes involved in the peripheral circulation,
9Describe the hemodynamic processes involved in the arterial and venous systems,
10Explain the factors affecting the regulation of blood flow and blood pressure,
11Describe the major structures, functions and regulatory systems involved in blood coagulation,
12Describe the anatomical and histological properties of the organs and structures involved in breathing and making up the airways,
13Describe the central and peripheral control mechanisms affecting respiration,
14Describe the basic concepts and understand the terminology concerning the structure and function of the lungs, and differentiate the normal values
15Describe the transports of oxygen and carbon dioxide in blood and process of gas exchange in the alveoli,
16To explain the structures and mechanisms related to ingest the food
17To explain the anatomy, histology and physiology of oral cavity , salivary glands, pharynx and esophagus
18To describe the anatomical and histological features of the stomach; to count and explain the functions of stomach such as mechanical mixing of food, enzymatic digestion, storage, absorption
19To explain the anatomical, histological features and functions of the small intestine and large intestine; to describe the anatomy and physiology of rectum and anal canal; to explain the anatomical, histological properties and functions of the liver, pancreas and gall bladder
20To describe the anatomic features of the portal system
21To describe the enzymatic reactions and mechanisms in the digestion and absorbtion of carbohydrates, proteins and fats, the composition and functions of lipoproteins in plasma; to explain the metabolic pathways and regulatuar mechanisms for synthesis and degradation of glycogen, fatty acids, tryglicerid, cholesterol, keton bodies.
22To describe the mechanism by which hormonal activation of lipolysis, lipogenesis, glycolysis (anaerobic/aerobic), glycogenesis, glycogenolysis, glyconeogenesis in liver and adipose tissue in the fasting and postprandial states, discuss the metabolic interrelationships between the organ and tissue; o describe the biochemical functions of liver; synthesis of plasma proteins and their roles/ their broad classification, the acute phase response and the change it induces in the concentrations of circulating plasma proteins, the biochemical degradation pathways of xenobiotics and dicuss the metabolic effects of alcohol consumption.
23To describe fat-soluble and water-soluble vitamins, trace metals discuss the actions and sources of vitamins, discuss signs and symptoms of vitamin deficiencies.
24To describe safety water and food in terms of health protection and promotion and to describe how access safety water, safety food and healthy eating affects the community health within the framework of causal relationship
25To describe measures of central tendency and distribution which can be used in the evaluation of community nutrition; to describe the importance of nutrition in terms of health protection and promotion and to arrange balanced diet, nutrition schemes for different groups and to calculate body mass index
26Be able to define the histological and anatomical structures of the central nervous system; explain the biochemical, physiological, biophysical and behavioral mechanisms of the interaction / communication of this primary homeostatic control system with the endocrine, immune, muscular and other organ systems from the molecular level to the system level, and realize their anaesthesiological and pharmacological significance
27Be able to define the histological and anatomical structures of the peripheral nervous system and explain their physiological, biochemical, biophysical and behavioral mechanisms
28Be able to define the histological and anatomical structures of the spinal and autonomic ganglia and explain their physiological, biochemical, biophysical and behavioral mechanisms.
29Be able to define the histological and anatomical structures of the sense (sensory) organs, the primary components of the interaction / communication between human and environment, and explain their physiological, biochemical, biophysical and behavioral mechanisms
30Be able to define the histological and anatomical structures of neuro-endocrine system, explain their physiological, biochemical, biophysical and behavioral mechanisms, and thoroughly comprehend homeostatic integration
31Comprehend the structure-function-behavior dimensions of the vital autonomous functions, sensory systems and pain, posture and motor regulations, emotions, drives and motivations, higher executive functions and consciousness
32Understand the foundations, and the physiological and clinical significance of neuroplasticity
33Be introduced to brain awareness and neuro-ethics briefly
34Explain the mechanisms which control the volume of the fluids in the body,
35Explain the physiological and biochemical principles of the balance between body fluid content and electrolytes,
36Understand the renal handling of water, proteins, non-protein nitrogen compounds, glucose and electrolytes in the process of urine formation,
37Describe the role of the kidneys on the basis of its anatomo-histological and physiological properties
38To explain the biochemical structure of Insulin, glucagon, POMC family, glucocorticoids, ACTH and adrenal cortex hormones and their roles on metabolism, describe the regulatory processes controlling the biosynthesis, transport and mechanism of action of thyroid hormones
39To explain the anatomical, histological features and functions of thyroid gland; to discuss the anatomical structures, functions and biochemical mechanisms in some pathological processes
40explaining the structure and endocrin functions of genital organs in adults, and the sexual functions along with the psychological aspects
41Defining the whole changes and developmental stages in babies and mothers during pregnancy
42Explaining whole structural, functional and psychological changes related to the triggering of birth in a woman that completed the pregnancy period, decrease in size of uterus due to contractions and baby s delivery to external environment
43Define the concepts of health and disease.
44List and classify the causes and factors of the disease.
45Explain the mechanisms of causes and factors of human disease.
46Explain the concepts of pre-diagnosis, differential diagnosis, and final diagnosis during the patient management process.
47Explain the basic principles of pharmacotherapy and classify the drug groups.
48Perform basic drug and suture applications on medical mannequin and models.
Mode of Delivery
Formal Education
Prerequisites and co-requisities
Recommended Optional Programme Components
Course Contents
MUSCLE AND NERVE TISSUES I. COMMITTEE Anatomy of skeletal muscles The histology of muscle tissue The histology of nerve tissue Introduction to the embryology and gametogenesis I. weeks of the development II. weeks of the development III. weeks of the development Embryologic period Fetal period Fetal membranes and placenta, congenital malformations The general and cellular organization of Nervous system, the action potential firing and conduction in excitable cells, synaptic entegration The structural properties, the fiber types, the energy metabolism, the contraction mechanism and the receptors of skeletal muscle The contraction properties of smoot muscle and cardiac muscle Biochemistry of muscle tissue Nervous tissue biochemistry Biochemistry of connective tissue Biochemistry of epithelial tissue General characteristics, contamination, clinical features, diagnosis and treatment of the arthropods Basic Adult Life Support Pediatric Life Support Choking BLOOD LYMPH CIRCULATION and THE IMMUNE SYSTEM II. COMMITTEE Peripheric artery, nerve and vein anatomy Blood histology Hematopoesis Histology of the lymphoreticular system Histology of spleen and thymus The properties of haemopoiesis The functions of red blood cells, white blood cells and platelets The blood groups, hemostasis and fibrinolysis Biochemistry of blood tissue Coagulation biochemistry Plazma proteins and ve immunoglobulins Clinical enzymology and tumor biochemistry The immune system The formation immune response Agents of superficial mycoses Candida albicans and other candida Systemic mycoses factors (Coccidioides, histoplazma, Chromoblastomycosis, Blastomyces) Opportunistik mycotic agents (Cryptococcus, Aspergillus, and mucoramycosis) In vitro combination of an antigen-antibody: Serological methods principles Serological methods of diagnosis of viral infections EIA, PCR, and new molecular diagnostic methods Identification and isolation of yeasts and molds (Practice) Serology: slide agglutination, Brucella agglutination. (Practice) The general characteristics, contamination, clinical features, diagnosis, treatment and preventions of the protozoons and trematodes living in the circulation of the blood-lymph The definition and evaluation of cardiac exam Examination of arterial tension and pulse Examination of the respiratory system CIRCULATORY AND RESPIRATORY SYSTEMS III. COMMITTEE Anatomy of the circulatory and respiratory systems The development of the respiratory system The histology of the respiratory system The development of the heart and vessels The histology of the heart and vessels Characteristics of the heart muscle, specialized excitatory and conductive system of the heart, electrocardiography, cardiac cycle and regulation of cardiac output Hemodynamics; flow, pressure and resistance properties and regulation The elastic properties of lungs and alveolar ventilation Pulmonary blood flow, gas exchange and transport Regulation of respiration Blood gases, respiration biochemistry and buffers Free radicals and antioxidants Staphylococci Streptococci and pneumococci Neiseria'lar: N. meningitidis, N. gonorrhoeae, M. Catharralis Legionella Corynebacterium Small gram-negative bacilli: Haemophilus bacteria Francisella and Pasteurella Bordetella and other coccobacillus L-form bacteria and Mycoplasma Mycobacteria: M. tuberculosis M. leprosy and other mycobacterium Actinomycetes and Nocardia Orthomyxoviruslar Paramyxoviruslar and Adenoviruses Pox Viruses Practice: Bacteriological media, sowing methods and throat cultures, Gram-positive cocci. (Practice) Evaluation of Cultures: Colony morphology and Gram staining, Gram-negative cocci Acid-fast staining, mycobacteria (Practice) The general characteristics of the blood and tissue nematodes , their contamination , clinical features, diagnosis and treatment Hand-washing, wearing sterile gloves DIGESTIVE SYSTEM AND METABOLISM IV. COMMITTEE Anatomy of the digestive system Embryology of the digestive system Histology of the upper digestive tract Histology of the lower digestive tract Liver histology Histology and the gallbladder and pancreas The properties and regulation of motor activity and secretion functions of gastrointestinal system. Digestion and absorption of carbohydrates, proteins and lipids Regulation of food intake Digestion and absorption of nutrients Regulation of blood sugar Diabetes biochemistry and OGTT Lipoprotein metabolism and atherosclerosis Laboratory OGTT Iron metabolism Adipose tissue biochemistry Disorders of amino acid and protein metabolisms Metabolism of phorphyrines and bile pigments Metabolic functions of liver and detoxification Xenobiotic metabolism Liquid electrolyte metabolism General properties of Enterobacteria Escherichia coli Klebsiella, Enterobacter Shigella Salmonella Vibrio Yersinia Brucella Anaerop spore-forming gram-positive bacilli Nonspore anaerop bacteria Anaerop spore-forming gram-positive bacilli: Clostridium Campylobacter and Helicobacter Pseudomonas and nonfermentative bacteria Picornaviruses: poliomyelitis, coxsackie, and ECHO viruses Hepatitis viruses HIV Biochemical properties of enterococci (Practice) Antibiogram, Gram-positive cocci (Practice) Gets information about the parasites that cause infections in the digestive system and knows the prevention methods Medical history and physical examination Emergency patients and approach NEUROCOMMITTEE V. COMMITTEE Anatomy of the nervous system The development of the nerve system The development and histology of the eye The development and histology of the ear The development and histology of the skin Neurotransmitters Perceiving and conduction of somatic and special senses CNS structures involved in the control of motor activity The hypothalamus and limbic system functions Physiology of learning, memory and sleep The autonomic nervous system functions CSF chemistry, separation of transudate and exudate Eye and Biochemistry of vision Apopitosis Spirochetes: Treponema pallidum Leptospira Borrelia and Spirochetes Arboviruses Slow Viruses Herpes viruses Gets information about the free pathogenic amoeba, recognizes the interference, knows its differential diagnosis and treatment Intravenous Injection Intramuscular Injection Forensic examination and forensic report writing ENDOCRİNE AND UROGENITAL SYSTEM VI. COMMITTEE Anatomy of the endocrine and reproductive systems Embryology of the urinary system Histology of the urinary system Embryology of the reproductive system Histology of the male reproductive system Histology of the female reproductive system Embryology and histology of the hypophysis and epiphysis Embryology and histology of the thyroid and parathyroid glands Embryology and histology of the adrenal glands Functional properties of the nephron Urine concentration and dilution; Acid-base balance General properties and action mechanisms of hormones Hypothalamohypophyseal system hormones Hormonal regulation of growth and development Thyroid hormones Pancreatic hormones Stress response: Endocrine mechanisms Fluid and electrolyte balance and endocrine control Calcium balance and endocrine control Male reproductive physiology The female reproductive physiology Thyroid hormones and disorders Kidney function tests Laboratory clearance Urinary biochemistry Laboratory (urine biochemistry) Hormones and disorders of calcium and phosphorus metabolism Disorders of steroid hormones in the gonads General structure and mechanisms of hormones Hypothalamus and hypophysis hormones and disorders Adrenal hormones and disorders Pancreas and GIS hormones and disorders The general characteristics of the Trichomonases , their contamination , clinical features, diagnosis and treatment BIOLOGICAL BASIS OF DISEASES VII. COMMITTEE The general characteristics of protozoon and helmints, their clinical features, diagnosis, treatment and prevention methods, Bacterial host interactions, pathogenicity and virulence, Rickettsiae and laboratory diagnosis of infections, Chlamydia and laboratory diagnosis of infections, Preanalytical factors affecting biochemical measurements. Biochemistry of pediatric and old age. Overview of Infectious Diseases, Introduction to Pharmacology, ADME Mechanism of action of drugs, Drug Receptors, Pharmaceutical Shapes, factors altering drug effects, Interactions Between Drugs, Prescription Writing, Dose Concentration-Response, Drug Application Paths, toxic effects of drugs and toxicology Basic Concepts, principles of first aid and emergency patients poisoned, Introduction to Pathology, Pathology of Inflammation, Morphology of Inflammation, Chronic Inflammation, Healing and Reperation, Defects of Healing and Repair, Oedema, Congestion and Hyperemia, Emboli,Infarctus, Trombus an dShock, Cell Injury and Death, Apoptosis, Pathology of Environmental Diseases, Adaptation, intracellularaccumulations, calcificationand degenerations
Weekly Detailed Course Contents
WeekTheoreticalPracticeLaboratory
1MUSCULUS and NERVE I. COURSE COMMITTEE ANATOMY Shoulder muscles Arm muscles Fossa axillaris - plexus brachialis Forearm and hand muscles Hip region muscles HISTOLOGY AND EMBRYOLOGY Muscle tissue histology Nerve tissue histology PHYSIOLOGY Dice potentials and action potentials MEDICAL BIOCHEMISTRY Bone and epithelial tissue biochemistry Muscle tissue biochemistryANATOMY Shoulder muscles Fossa axillaris - plexus brachialisHISTOLOGY AND EMBRYOLOGY Muscle tissue histology
2ANATOMY Hip region muscles Thigh locus muscles Sacral lumbar pudendal plexus PHYSIOLOGY General organization of the nervous system Sensory receptors Excitation of skeletal muscle HISTOLOGY AND EMBRYOLOGY Introduction to embryology and gametogenesis Week 1 of DevelopmentANATOMY PRACTICAL - Forearm and hand muscles Thigh locus musclesHISTOLOGY AND EMBRYOLOGY Nerve tissue histology
3ANATOMY Muscles of the leg and foot regions Back and neck muscles HISTOLOGY AND EMBRYOLOGY Week 1 of Development Week 2 of Development FİZYOLOJİ Skeletal muscle contractionCLINICAL SKILLS EDUCATION Pediatric life support ANATOMY PRACTICE - Muscles of the leg and foot region Sacral lumbar pudendal plexus
4ANATOMY Chest wall muscle and its formation Neck muscles HISTOLOGY AND EMBRYOLOGY Embryonic period PHYSIOLOGY Sports physiology: muscles in exerciseANATOMY Chest and abdominal muscles and inguinal region CLINICAL SKILLS EDUCATION PRACTICAL - Basic life support in adultsPHYSIOLOGY PRACTICE Electromyography (EMG) Muscle message speed
5ANATOMY Facial muscles Practice Exam - Anatomy KAS AND NERVE DOCUMENTS I. COURSE COMMITTEE THEORETICAL EXAMANATOMY PRACTICAL - Neck muscles Facial muscles
6BLOOD-LENF CIRCULATION AND IMMUNITY SYSTEM II. COURSE COMMITTEE ANATOMY Upper limb peripheral structures Lower extremity peripheral structures PHYSIOLOGY Introduction to blood physiology, blood structure and functional properties hematopoesis MEDICAL BIOCHEMISTRY Plasma proteins and immunglobulins HISTOLOGY AND EMBRYOLOGY Blood histology MEDICAL MICROBIOLOGY Basic concepts of immunology and immune system cells Superficial, cutaneous and subcutaneous mycoses PARASITOLOGY Diagnostic methods in parasitology laboratory, operation and applicationsANATOMY Upper limb peripheral structures CLINICAL SKILLS TRAINING PRACTICAL: İ.V Blood collection
7ANATOMY Peripheral structures of the neck region Peripheral structures of the face region Physiology erythrocytes PARASITOLOGY Preparation of thin blood thin thick blood preparations, painting with Giemsa HISTOLOGY AND EMBRYOLOGY hematopoesisANATOMY PRACTICAL - Lower extremity peripheral structures Peripheral structures of the neck region Peripheral structures of the face region CLINICAL SKILLS TRAINING PRACTICAL: Vessel path openingHISTOLOGY AND EMBRYOLOGY PRACTICE Blood histology PARASITOLOGY Preparation of thin blood thin thick blood preparations, painting with Giemsa
8HISTOLOGY AND EMBRYOLOGY Lymphoid system histology Spleen and thymus histology MEDICAL BIOCHEMISTRY Coagulation biochemistry Blood biochemistry PHYSIOLOGY Blood groups Anemia and polymyositis MEDICAL MICROBIOLOGY Systemic (endemic) mycoses Opportunistic mycoses-1 Opportunistic mycoses-2 Opportunistic mycoses-3HISTOLOGY AND EMBRYOLOGY Lymphoid system histology Spleen and thymus histology PARASITOLOGY PRACTICAL The construction of fine-grained thick-drop blood reparations,                          Painting with Giemsa
9PHYSIOLOGY Leukocytes; general features granulocytes lymphocytes platelets PARASITOLOGY Blood living whistles (visceral and cutaneous leishmaniasis) Toxoplasmosis Plasmodiums, Babesia, Trypanosomae MEDICAL MICROBIOLOGY PCR and new molecular diagnostic methods Marked solid phase methods: ELISA and IFA Serological diagnostic methods in viral infections PHYSIOLOGY PRACTICE Erythrocyte count, hemoglobin and hematocrit, sedimentation -Leukocyte count, leukocyte formula, blood groups, bleeding-clotting time MEDICAL MICROBIOLOGY PRACTICAL Isolation of yeasts and molds - Identification Serological tests
10Practice Exam - Anatomy BLOOD - LENF FREQUENCY AND IMMUNITY SYSTEMS II. THEORETICAL EXAMINATIONPARASITOLOGY PRACTICE Leishmania, Plasmodium, Trypanosoma, Toxoplasma
11CIRCULATION AND RESPIRATORY SYSTEMS III. COURSE COMMITTEE ANATOMY Chest cavity, diaphragma and pleura Mediastinum and its formations Kalbin outer face, location, projection, pericardium HISTOLOGY AND EMBRYOLOGY Development of heart and vessels Cardiovascular histology PARASITOLOGY Toxocora species and parasites, Trichinella spiralis and Larva migrans Filarians, W. bancrofti, D. medinensis, D. conc. Liver trematodes MEDICAL MICROBIOLOGY Piyogenic SMEs: Staphylococci Streptococci and pneumococci PHYSIOLOGY Introduction to cardiovascular system physiology Properties of the heart muscle Heart-specific messaging systemANATOMY PRACTICAL - Chest cavity, diaphragma and pleuraHISTOLOGY AND EMBRYOLOGY Cardiovascular histology
12ANATOMY Internal surface of heart, veins, nerves Aorta, truncus pulmonalis, V. cava superior, fetal circulation Physiology electrocardiogram Heart cycle hemodynamics MEDICAL MICROBIOLOGY Neisseria: N. meningitidis, N. gonorrhoeae, N. catharralis Legionella KorineBacteria Small gram negative bases: Hemophil bacteria Francisella and Pasteurella Bordetella and other cocobacillas Mycoplasma and L-form bacteria MEDICAL BIOCHEMISTRY Blood gases, respiratory biochemistry, buffers HISTOLOGY AND EMBRYOLOGY Development of respiratory systemANATOMY PRACTICAL - heart outer face, location, projection, pericardium -ANATOMY Internal surface of heart, veins, nerves - Large vessels, large, small and fetal circulationPHYSIOLOGY PRACTICE Circulatory system applications
13Physiology microcirculation Regulation of blood pressure Regulation of the heart valve Special circulation Heart failure HISTOLOGY AND EMBRYOLOGY Respiratory system histology MEDICAL MICROBIOLOGY Actinomycetes and Nocardia ANATOMY Cavum nasi and paranasal sinuses Larinks PARASITOLOGY Lung and blood trematodes Infections affecting cestodes, Echinococcosis, Rhinosporidiasis MEDICAL BIOCHEMISTRY Free radicals and antioxidantsHISTOLOGY AND EMBRYOLOGY Respiratory system histology
14ANATOMY Trachea, lung, respiration MEDICAL MICROBIOLOGY Mycobacteria: M. Tuberculosis M. lepra and other mycobacteria Orthomyxovirus on Paramyxoviruses and Adenoviruses Pox viruses PHYSIOLOGY Disorders of heart valve Circulation odor Introduction to ventilation and respiratory system Compliance of the lungs Pulmonary circulation Lung volume and capacities Respiratory membrane Carriage of oxygen and carbon dioxide Respiratory regulation OPTIONAL LESSON ANATOMY Trachea, lung, respirationPARASITOLOGY PRACTICE - Trematodlar, Echinococcosis
15PHYSIOLOGY Height and underwater physiology Exuberance circulation and adaptation of the respiratory system Respiratory failure physiopathology Practice Exam - Anatomy CIRCULATION AND RESPIRATORY SYSTEMS III.CODE COMMITTEE THEORETICAL EXAMPHYSIOLOGY PRACTICE - Respiratory function tests
16MEDICAL MICROBIOLOGY General characteristics of Enterobacteriacea Escherichia coli Shigella Salmonella PHYSIOLOGY Introduction to GIS physiology GIS hormones PARASITOLOGY Fecal examination methods Giardia intestinalis, infectious agents in the intestine, other protozoons E. histolytica, other amiplers B. hominis, Microsporidialar, Cryptosporidium, İsospora, Cylospora, Sarcocystis, Balantidium HISTOLOGY AND EMBRYOLOGY Digestive system embryology MEDICAL BIOCHEMISTRY Regulation of blood sugar and biochemistry of diabetes Metabolic functions of the liver and detoxificationPARASITOLOGY PRACTICAL - G. intestinalis, E. histolytica, B. hominis, Microsporidae, Cryptosporidium, Isospora, Cylospora
17PHYSIOLOGY Enteric nervous system Anatomy Back wall anatomy Oral cavity, tongue, teeth, fossa retromandibularis, salivary glands MEDICAL BIOCHEMISTRY Metabolism of xenobiotics Disorders of amino acid and protein metabolism MEDICAL MICROBIOLOGY Yersinia and other Enterobacteriaceae species Vibrio HISTOLOGY AND EMBRYOLOGY Upper gastrointestinal system histology PARASITOLOGY D. latum, H. nana, H. DimminutaAnatomy Back wall anatomy Oral cavity, tongue, teeth, fossa retromandibularis, salivary glands
18ANATOMY Pharynx and esophagus anatomy Stomach anatomy Pancreas and spleen anatomy Thin small intestines PARASITOLOGY Taenia saginata, Taenia solium, intestinal trematodes Hookworms, T. Trichura MEDICAL MICROBIOLOGY Pseudomonas and other nonfermentative bacteria Brucella PHYSIOLOGY General characteristics of GIS motility, chewing, swallowing Stomach motility HISTOLOGY AND EMBRYOLOGY Lower gastrointestinal system histology MEDICAL BIOCHEMISTRY Iron metabolism TIBBI BIOCHEMISTRY Iron metabolism ANATOMY Pharynx and esophagus anatomyHISTOLOGY - Upper gastrointestinal system histology MEDICAL BIOCHEMISTRY PRACTICE OGTT
19MEDICAL BIOCHEMISTRY Porphyrins and bile pigments ANATOMY Thick intestines and anus Liver and biliary anatomy PARASITOLOGY Ascaris lumbricoides, Enterobius vermicularis, S. stercoralis PHYSIOLOGY Pancreas and bile secretion Digestion and absorption of carbohydrates Digestion and absorption of fats HISTOLOGY AND EMBRYOLOGY Liver histologyANATOMY PRACTICE - Stomach, pancreas and spleen anatomyHISTOLOGY - Histology of the lower digestive system MEDICAL BIOCHEMISTRY PRACTICE Bilirubin appointment
20HISTOLOGY AND EMBRYOLOGY Bile duct and pancreas histology MEDICAL BIOCHEMISTRY Liquid electrolyte metabolism PHYSIOLOGY Liver functions Regulation of body temperature Regulation of nutrient uptake MEDICAL MICROBIOLOGY Anaerobic spore gram positive bacilli: Clostridiums Picornaviruses: Poliomyelitis, Koksaki and ECHO viruses MEDICAL BIOCHEMISTRY Fatty biochemistry Lipoprotein metabolism and atherosclerosisANATOMY PRACTICE - Anatomy of the liver and bileHISTOLOGY AND EMBRYOLOGY PRACTICE Liver, gall bladder, pancreas and salivary glands
21MEDICAL MICROBIOLOGY Hepatitis viruses HIV MEDICAL BIOCHEMISTRY Lipoprotein metabolism and atherosclerosis Practice Exam - Anatomy DIGESTION AND METABOLISM IV. COURSE COMMITTEE THEORETICAL EXAMHISTOLOGY AND EMBRYOLOGY PRACTICE Liver, gall bladder, pancreas and salivary glands MEDICAL MICROBIOLOGY PRACTICE - Biochemical characteristics of Enterobacter
22NÖROKOMİT to V. COURSE COMMITTEE PHYSIOLOGY Touch and status senses MEDICAL BIOCHEMISTRY CSF biochemistry, transudate - exudate separation ANATOMY Medulla spinalis morphology and spinal nerve formation HISTOLOGY AND EMBRYOLOGY Nervous system development MEDICAL MICROBIOLOGY Spirochetes: Treponema pallidum MEDICAL BIOCHEMISTRY Eye and vision biochemistryANATOMY PRACTICE - Medulla spinalis morphology and spinal nerve formationHISTOLOGY AND EMBRYOLOGY PRACTICE - Eye development and histology
23ANATOMY Cerebellum and mesencephalon morphology Head pairs Diencephalon PHYSIOLOGY Receptor and neural function of retinas Hearing sense MEDICAL MICROBIOLOGY Borrelia and other spirochetes arbovirus on HISTOLOGY AND EMBRYOLOGY Ear development and histologyANATOMY PRACTICAL - Bulbus, pons, cerebellum and mesencephalon morphology
24MEDICAL MICROBIOLOGY Slow viruses rickettsiae PHYSIOLOGY Taste and smell ANATOMY Basal ganglia ANATOMY Medulla spinalis pathways Rhinencephalo's Anatomy PHYSIOLOGY The motor functions of the spine MEDICAL MICROBIOLOGY Herpes virusesANATOMY PRACTICE - Telencephalon and ventricular systemPHYSIOLOGY PRACTICE - Hearing and vision tests
25ANATOMY Bulbus, pons routes Autonomic nervous system Autonomic nervous system Mesencephalon, cerebellum, telencephalon and diencephalon pathways HISTOLOGY AND EMBRYOLOGY Skin histologyPHYSIOLOGY PRACTICE - Reflexes HISTOLOGY AND EMBRYOLOGY PRACTICE - Skin histology
26ANATOMY Eye anatomy PHYSIOLOGY Mechanisms of brain's behavior and motivation Activity states of the brain MEDICAL BIOCHEMISTRY ApoptosisANATOMY PRACTICE - Brain membranes and veins Eye anatomy
27MEDICAL MICROBIOLOGY Chlamydia PHYSIOLOGY Brain blood flow ANATOMY PRACTICE - General repetition Practice Exam - Anatomy NÖROKOMİTE V. COURSE COMMITTEE THEORETICAL EXAMPHYSIOLOGY PRACTICE - Electroencephalography (EEG)
28ENDOCRINE AND UROGENITAL SYSTEMS VI. COURSE COMMITTEE
29HISTOLOGY AND EMBRYOLOGY Urinary system embryology ANATOMY Anatomy of the kidney, ureter and bladder Diaphragm pelvis and diaphragm urogenitale MEDICAL BIOCHEMISTRY Kidney function tests PHYSIOLOGY Duties of the kidney, bloodshed, nephron structure and typesANATOMY PRACTICE - Kidney, ureter and bladder anatomy
30PHYSIOLOGY Glomerular filtration rate Proximal tubule HISTOLOGY AND EMBRYOLOGY Histology of female genital system ANATOMY Female external genital organsANATOMY PRACTICAL - Male genital organsHISTOLOGY Urinary system histology PRACTICE MEDICAL BIOCHEMISTRY PRACTICE - Clearance HISTOLOGY PRACTICE - Histology of female genital system MEDICAL BIOCHEMISTRY PRACTICE - Urine biochemistry
31ANATOMY Endocrine glands HISTOLOGY AND EMBRYOLOGY Embryology and histology of the pituitary and pineal glands MEDICAL BIOCHEMISTRY General structure and effect mechanisms of hormones PHYSIOLOGY Acid - base balance Diuretics, Kidney diseases Mechanisms of action of hormones Mechanisms of action of hormones Hypothalamic hypophyseal system Endocrine control of growth HISTOLOGY AND EMBRYOLOGY Embryology and histology of thyroid and parathyroid glands Embryology and histology of adrenal glands MEDICAL BIOCHEMISTRY Hypothalamus and pituitary hormones and disorders ANATOMY PRACTICE - Endocrine glands
32MEDICAL BIOCHEMISTRY Hormones and disorders that regulate calcium and phosphate metabolism Adrenal hormones and disorders PHYSIOLOGY Thyroid hormones Endocrine control of fluid-electrolyte balance Endocrine control of calcium and phosphate metabolism Pancreas and GIS hormones and disorders
33MEDICAL BIOCHEMISTRY Steroid hormones and disorders of the gonads PHYSIOLOGY Physiology of pregnancy and lactation ENDOCRINE AND UROGENITAL SYSTEMS VI. COURSE COMMITTEE THEORETICAL EXAMHISTOLOGY AND EMBRYOLOGY PRACTICE (A) - Endocrine system histology
34MEDICAL MICROBIOLOGY Immunology Introduction and Immune System Natural immunity - host defense mechanisms MEDICAL PHARMACOLOGY Introduction to pharmacology Interactions between drugs Factors that change the effect of drugs Dose concentration - Response Drug receptor association Mechanisms of action of drugs MEDICAL PATHOLOGY Introduction to pathology Cell damage and death -1 Cell damage and death II
35TIBBİ PATOLOJİ Kronik iltihap –I Kronik iltihap –II İyileşme ve tamir onarım kusurları –I İyileşme ve tamir onarım kusurları –II Ödem, konjesyon ve hiperemi Emboli, infarktus, trombus, şok TIBBİ MİKROBİYOLOJİ İmmün yanıtın oluşumu TIBBİ BİYOKİMYA Klinik enzimolojiKLİNİK BECERİ EĞİTİMİ İ.V Kan alma
36KURUL SINAVI
Recommended or Required Reading
Anatomi Cilt 1 ve Cilt 2 (Prof.Dr. Kaplan Arıncı, Prof.Dr. Alaittin Elhan) Sobotta İnsan Anatomisi Atlası Cilt 1 ve Cilt 2 (Prof.Dr. Kaplan Arıncı, Prof.Dr. Alaittin Elhan) Temel Klinik Anatomi (Moore Çevirisi) (Prof.Dr. Alaittin Elhan) Fonksiyonel Anatomi : Baş Boyun Ve İç Organlar( Prof. Dr. Bedia SANCAK, Prof. Dr. Meserret CUMHUR) Fonksiyonel Anatomi : Ekstremiter ve Sırt Bölgesi ( Prof. Dr. Doğan Taner) Temel Histoloji Yazar: Luiz C. JUNQEIRA-Jose CARNEIRO Çeviri Editörleri: Yener AYTEKİN, Seyhun SOLAKOĞLU Yayınevi: Nobel Tıp Kitabevi. Langman Medikal Embriyoloji Yazar: Thomas W. Sadler Çeviri Editörü: A. Can BAŞAKLAR Yayınevi: Palme Kitabevi. Fonksiyonel İlişkileriyle diFiore Histoloji Atlası Yazar : Victor P. EROSCHENKO Çeviri Editörü: Ramazan DEMİR Yayınevi: Palme Kitabevi. Kierszenbaum AL, Tres LL. Histology and Cell Biology. 3rd edition Philadelphia: Elsevier Saunders; 2012. Gardner LP, Hiatt JL. Color Textbook of Histology. Philadelphia: WB Saunders Company; 1997. Ross MH, Pawlina W. Histology. A Text and Atlas. 6th edition. Philadelphia, LWW; 2011. Junqueira LC, Carneiro J. Basic Histology, 13th edition New York, McGraw-Hill Companies; 2013. Young B, Lowe JS, Stevens A, Heath JW. Wheater's Functional Histology: A Text and Colour Atlas. 5th edition. China, Churchill Livingstone; 2006. Moore KL, Persaud TVN. The Developing Human, Clinically Oriented Embryology. WB Saunders Company; 2009. Eroschenko VP, DiFiore's Atlas of Histology with Functional Correlations, 11th edition, Lippincott Williams & Wilkins, 2008. Guyton Medical Physiology Ganong’s Medical Physiology Physiology; Berne & Levy R.K. Murray, Harper Biyokimya Harvey, Champe, Lippincott Biyokimya N.V. Bhagavan, Medical Biochemistry D.N. Lehninger, Principles of Biochemistry B.Adam ,Y.Ardıç, Klinik Biyokimya Analiz Metodları İ.Mehmetoğlu , Klinik Biyokimya Laboratuvarı El Kitabı K.M.Ringsrud, urinalysis and body fluids G.B.Fogazzi, İdrar sediment Murray PR, Baron EJ, Jorgensen JH, Landry ML, Pfaller MA. Manual of Clinical Microbiology: Washington, DC. Roitt`s Temel İmmünoloji Özel Bakteriyoloji ve Bakteri Enfeksiyonları. Hakkı Bilgehan Klinik Mikrobiyoloji . Kılıçturgay K, Gökırmak F, Töre O, Gedikoğlu S, Göral G, Helvacı S. Özcel M.A. Özcel’in Tıbbi Parazit Hastalıkları, 2007, Meta basım, İzmir. http://www.tkd-online.org/dergi/TKDA_39_70_1_34.pdf Intravenous injection model, angiocath, tourniquet, syringe, antiseptic solution, gloves Intramuscular injection model, The Heart İnternal medicine A.W. TOPÇU , G. SÖYLETİR; Infectious Diseases and Clinical Microbiology M. DOĞANAY; Hospital İnfectious 2013 V. Aleksanyan, From symptoms to diagnosis, Kliegman, Stanton, St. Geme, Schor, Behrman, Nelson Textbook of Pediatrics O. Neyzi, T. Ertuğrul, Pediatrics Harrison Internal Medicine editor: E. Braunwald, A. S. Fauci İLİÇİN Internal medicine Editor : İnci Süleymanlar, Gürler İliçin, Kadir Biberoğlu Textbook of public health (Prof.Dr.Sevim Yumuturuğ) Basic knowledge of public health ( Prof.Dr. Münevver Bertan, Doç.Dr. Çağatay Güler)
Planned Learning Activities and Teaching Methods
Assessment Methods and Criteria
Term (or Year) Learning ActivitiesQuantityWeight
SUM0
End Of Term (or Year) Learning ActivitiesQuantityWeight
SUM0
Yarıyıl (Yıl) İçi Etkinlikleri60
Yarıyıl (Yıl) Sonu Etkinlikleri40
SUM100
Language of Instruction
Turkish
Work Placement(s)
Workload Calculation
ActivitiesNumberTime (hours)Total Work Load (hours)
Midterm Examination616
Final Examination122
Attending Lectures9501950
Practice4501450
Self Study2401240
Individual Study for Mid term Examination61272
Individual Study for Final Examination13232
TOTAL WORKLOAD (hours)1752
Contribution of Learning Outcomes to Programme Outcomes
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PO
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* Contribution Level : 1 Very low 2 Low 3 Medium 4 High 5 Very High
 
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